From Philadelphia – 676W
- Slight left at 1-676 W
- Take exit towards Central Phila
- Turn right at N 15th St
- Turn left at PA-3/PA-611/S Penn Square
- Turn right at S Broad St/Ave of the Arts/PA-611
- Turn left onto South St to 1020 South Street
From Northern Locations: New York, Connecticut, North Jersey
- Interstate 95 south to exit 676 west/ 30 Vine Street expressway Callowhill Street: Central Philadelphia Independence Hall
- Head west on Callowhill Street toward N 11th St.
- Turn left at N Broad Street/PA-611, continue to follow N Broad Street
- Slight right at John F Kennedy Blvd/PA-3/PA-611
- Turn left at N 15th St/PA-611
- Turn left at PA-3/PA-611/ S Penn Square
- Turn Right at S Broad St/ Ave of the Arts/PA-611 continue to follow S Broad St/PA-611
- Turn left at South Street to 1020 South Street
From Pittsburgh, Harrisburg, Western Suburbs, Valley Forge, King of Prussia
- I-76E to Philadelphia.
- Take exit 24 for PA-202/I-476/I-76 toward Philadelphia
- Merge onto I-76 E
- Sight left at 1-676 W
- Take exit towards Central Phila
- Turn right at N 15th St
- Turn left at PA-3/PA-611/S Penn Square
- Turn right at S Broad St/Ave of the Arts/PA-611
- Turn left onto South St to 1020 South Street
From Southern Locations: Baltimore, Washington
- Take I-95 North to 676W
- Follow directions from 676W (above)
From South Jersey/Atlantic City
- Proceed to Benjamin Franklin Bridge. Cross bridge and merge onto 676W.
- Follow directions from 676W (above)
